Hong Xu Selected Research

Tacrolimus (Prograf)

1/2022	Effects of Posaconazole on Tacrolimus Population Pharmacokinetics and Initial Dose in Children With Crohn's Disease Undergoing Hematopoietic Stem Cell Transplantation.
1/2022	Population pharmacokinetics and initial dose optimization of tacrolimus in children with severe combined immunodeficiency undergoing hematopoietic stem cell transplantation.
9/2021	Effects of voriconazole on population pharmacokinetics and optimization of the initial dose of tacrolimus in children with chronic granulomatous disease undergoing hematopoietic stem cell transplantation.
8/2020	Population pharmacokinetics model and initial dose optimization of tacrolimus in children and adolescents with lupus nephritis based on real-world data.
5/2020	Initial dosage optimization of tacrolimus in Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics.
5/2020	Optimization of initial dosing scheme of tacrolimus in pediatric refractory nephrotic syndrome patients based on CYP3A5 genotype and coadministration with wuzhi-capsule.
4/2020	Initial dose optimization of tacrolimus for children with systemic lupus erythematosus based on the CYP3A5 polymorphism and coadministration with Wuzhi capsule.
12/2019	Tacrolimus increases the expression level of the chemokine receptor CXCR2 to promote renal fibrosis progression.
12/2019	Population pharmacokinetics of tacrolimus in pediatric patients with systemic-onset juvenile idiopathic arthritis: Initial dosage recommendations.

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Hong Xu Research Topics

Disease

181	Neoplasms (Cancer) 05/2024 - 09/2002
53	Infections 02/2024 - 09/2005
47	Inflammation (Inflammations) 04/2024 - 02/2012
45	Fibrosis (Cirrhosis) 04/2024 - 06/2007
37	Silicosis 04/2024 - 01/2012
35	Breast Neoplasms (Breast Cancer) 03/2024 - 11/2006
31	Proteinuria 11/2023 - 05/2007
29	Endometriosis 05/2024 - 06/2005
28	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 02/2006
27	Neoplasm Metastasis (Metastasis) 01/2023 - 07/2002
24	Pain (Aches) 12/2023 - 11/2009
23	Nephrotic Syndrome (Syndrome, Nephrotic) 05/2024 - 06/2005
21	Neuralgia (Stump Neuralgia) 03/2021 - 01/2012
20	Wounds and Injuries (Trauma) 05/2024 - 10/2013
20	Carcinogenesis 10/2023 - 07/2002
19	Body Weight (Weight, Body) 11/2023 - 01/2013
18	Carcinoma (Carcinomatosis) 10/2023 - 11/2005
17	Dementia (Dementias) 04/2024 - 01/2020
17	Chronic Renal Insufficiency 04/2024 - 08/2014
17	COVID-19 03/2024 - 01/2020
16	Ovarian Neoplasms (Ovarian Cancer) 03/2024 - 07/2007
16	Insulin Resistance 01/2024 - 03/2011
15	Stomach Neoplasms (Stomach Cancer) 05/2024 - 04/2012
15	Brain Ischemia (Cerebral Ischemia) 02/2024 - 12/2012
14	Kidney Diseases (Kidney Disease) 01/2024 - 03/2011
13	Hyperalgesia 01/2019 - 04/2016
12	Stroke (Strokes) 05/2024 - 12/2011
12	Hypertension (High Blood Pressure) 04/2024 - 03/2008
12	Atherosclerosis 04/2024 - 08/2007
12	Ischemic Stroke 01/2023 - 01/2014
12	Pancreatic Neoplasms (Pancreatic Cancer) 12/2021 - 10/2008
11	Cakut 04/2024 - 01/2019
11	Type 2 Diabetes Mellitus (MODY) 04/2024 - 01/2008
11	Myocardial Infarction 03/2024 - 04/2010
11	Tauopathies 03/2024 - 01/2014
11	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2023 - 09/2013
11	Reperfusion Injury 01/2023 - 12/2012
11	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2023 - 12/2011
11	Parkinson Disease (Parkinson's Disease) 01/2023 - 08/2009
11	Colorectal Neoplasms (Colorectal Cancer) 09/2022 - 01/2006
10	Hepatocellular Carcinoma (Hepatoma) 02/2024 - 07/2002
10	Hemorrhage 12/2023 - 08/2011
10	Lung Neoplasms (Lung Cancer) 03/2023 - 10/2008
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 01/2012
9	Adenocarcinoma 04/2024 - 08/2014
9	Obesity 04/2024 - 01/2018
9	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2022 - 01/2020
9	Liver Neoplasms (Liver Cancer) 01/2018 - 09/2011
8	Adenomyosis 01/2024 - 05/2009
8	Acute Kidney Injury (Acute Renal Failure) 12/2023 - 01/2017
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2023 - 10/2008

Drug/Important Bio-Agent (IBA)

96	Proteins (Proteins, Gene)FDA Link 04/2024 - 07/2002
43	Biomarkers (Surrogate Marker)IBA 01/2024 - 09/2012
32	Messenger RNA (mRNA)IBA 07/2023 - 04/2007
28	Silicon Dioxide (Silica)FDA LinkGeneric 04/2024 - 05/2014
21	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 05/2008
21	CreatinineIBA 01/2024 - 06/2011
21	MicroRNAs (MicroRNA)IBA 10/2023 - 08/2009
20	Glucose (Dextrose)FDA LinkGeneric 05/2024 - 01/2008
20	Therapeutic UsesIBA 02/2024 - 02/2008
19	Small Interfering RNA (siRNA)IBA 01/2022 - 06/2013
18	LipidsIBA 03/2024 - 03/2011
17	EnzymesIBA 01/2024 - 06/2005
17	CytokinesIBA 11/2023 - 01/2006
17	Long Noncoding RNAIBA 01/2023 - 03/2016
16	Interleukin-6 (Interleukin 6)IBA 02/2023 - 01/2006
16	Peptides (Polypeptides)IBA 01/2022 - 07/2012
15	goralatideIBA 10/2023 - 01/2012
13	Insulin (Novolin)FDA Link 01/2024 - 09/2004
13	CollagenIBA 12/2023 - 01/2012
13	Immunoglobulin G (IgG)IBA 01/2022 - 01/2015
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 09/2002
12	AntigensIBA 04/2024 - 01/2010
12	C-Reactive ProteinIBA 01/2024 - 06/2013
12	HydrogelsIBA 12/2023 - 11/2014
12	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2023 - 06/2008
12	Purinergic P2X3 ReceptorsIBA 09/2019 - 01/2012
10	Hormones (Hormone)IBA 05/2024 - 01/2003
10	RNA (Ribonucleic Acid)IBA 10/2023 - 06/2006
9	Blood Glucose (Blood Sugar)IBA 06/2024 - 01/2008
9	Fibrinogen (Factor I)FDA Link 11/2023 - 05/2015
9	CateninsIBA 10/2023 - 03/2013
9	AlbuminsIBA 04/2023 - 03/2012
9	VaccinesIBA 01/2023 - 09/2005
9	salicylhydroxamic acid (SHAM)IBA 01/2023 - 01/2014
9	Tacrolimus (Prograf)FDA LinkGeneric 01/2022 - 12/2019
9	Purinergic P2X7 ReceptorsIBA 01/2019 - 04/2016
8	AntioxidantsIBA 01/2024 - 04/2010
8	Transcription Factors (Transcription Factor)IBA 12/2023 - 01/2004
8	CholesterolIBA 12/2023 - 01/2013

Therapy/Procedure

124	Therapeutics 05/2024 - 01/2005
30	Drug Therapy (Chemotherapy) 04/2024 - 11/2006
17	Electroacupuncture 01/2023 - 07/2007
14	Knee Replacement Arthroplasty (Total Knee Replacement) 11/2023 - 11/2018
11	Chinese Traditional Medicine (Traditional Chinese Medicine) 04/2024 - 01/2005
10	Immunotherapy 04/2024 - 08/2009
10	Precision Medicine 05/2023 - 10/2009
8	Radioimmunotherapy 01/2023 - 08/2009
8	Peritoneal Dialysis 01/2023 - 06/2013
8	Aftercare (After-Treatment) 01/2023 - 10/2008